Bare Lymphocyte Syndrome (BLS) /Rare case Diagnosed in alnajaflab-Dr.Sabah Al Fatlawi

Bare Lymphocyte Syndrome (BLS) can be caused by deficiencies in either MHC class I or class II proteins. • BLS Type I: A rarer, milder form caused by a lack of MHC class I molecules. This leads to a deficiency in CD8+ T cells, resulting in recurrent bacterial respiratory infections and skin ulcers. • BLS Type II: The more common, severe form caused by a lack of MHC class II molecules. This results in a severe deficiency of CD4+ T cells, leading to life-threatening opportunistic infections.

نُشر بتاريخ: 2025-09-19 22:27:02

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Immunodeficiency 89 (IMD89)/Diagnosed in alnajaflab/Dr.Sabah Al Fatlawi

The clinical manifestations of IMD89 can include hypogammaglobulinemia, allergies, inflammatory bowel disease, and autoimmune cytopenias, reflecting the complex disruption of the immune system.

نُشر بتاريخ: 2025-09-19 00:27:40

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Wiskott-Aldrich Syndrome (WAS)/Diagnosed in alnajaflab/Dr,Sabah Al Fatlawi

Wiskott-Aldrich syndrome (WAS) is a rare, inherited immunodeficiency disorder that affects primarily males. It's characterized by a triad of symptoms: low platelet count, which leads to bleeding and easy bruising; frequent and recurrent infections; and eczema. The most effective treatment is a hematopoietic stem cell transplant

نُشر بتاريخ: 2025-09-18 22:55:01

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